Search on: LONG-TERM SYNAPTIC DEPRESSION 
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Descriptor English:   Long-Term Synaptic Depression 
Descriptor Spanish:   Depresión Sináptica a Largo Plazo 
Descriptor Portuguese:   Depressão Sináptica de Longo Prazo 
Synonyms English:   Depotentiation
Homosynaptic Depression  
Tree Number:   G11.561.600.635.355
Definition English:   A persistent activity-dependent decrease in synaptic efficacy between NEURONS. It typically occurs following repeated low-frequency afferent stimulation, but it can be induced by other methods. Long-term depression appears to play a role in MEMORY. 
Indexing Annotation English:   note category: do not confuse with clinical DEPRESSION or DEPRESSIVE DISORDERS
History Note English:   2008 (2003) 
Allowable Qualifiers English:  
DE drug effects ES ethics
GE genetics IM immunology
PH physiology RE radiation effects
Record Number:   37661 
Unique Identifier:   D036881 

Occurrence in VHL:
 

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